Plevitrexed (ZD 9331, BGC 9331) is an orally active and potent thymidylate synthase (TS) inhibitor with a Ki of 0.44 nM. Plevitrexed is taken up via the alpha-folate receptor as well as the reduced folate carrier. Plevitrexed is used for gastric cancer in clinical[1][2][3]. Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Molecular Weight:
532.53
Purity:
99.35
CAS Number:
[153537-73-6]
Formula:
C26H25FN8O4
Target:
Thymidylate Synthase
Application Notes:
MCE Product type: Reference compound
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