SK-3-91 is a PROTAC-type multi-kinase degrader that can jointly induce the degradation of the largest number of unique kinases (more than 125 unique kinases). SK-3-91 induces protein degradation through the ubiquitin biotinylation (E-STUB) pathway. SK-3-91 degrades YTHDF2. SK-3-91 inhibits cell proliferation and induces morphological changes. (Pink: TAE648 ligand (HY-169396), Blue: E3 ligase ligand (HY-131717), Black: Linker (HY-140819). The E3 ligase ligand and linker can form a conjugate (HY-169397))[1][2].
Molecular Weight:
887.40
Purity:
98.33
CAS Number:
[2769753-23-1]
Formula:
C42H47ClN10O8S
Target:
PROTACs,YTHDF
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
