Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research[1][2].
Molecular Weight:
406.45
Purity:
98.11
CAS Number:
[1681017-83-3]
Formula:
C23H23FN4O2
Target:
PARP
Application Notes:
MCE Product type: Reference compound
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