NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination[1].
Molecular Weight:
713.13
Purity:
95
CAS Number:
[2739805-63-9]
Formula:
C36H60N2O4S4
Target:
Endogenous Metabolite,Liposome
Application Notes:
MCE Product type: Oligonucleotides
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