Ebselen (SPI-1005), a glutathione peroxidase mimetic, is a potent voltage-dependent calcium channel (VDCC) blocker[1][2]. Ebselen potently inhibits Mpro (IC50=0.67 µM) and COVID-19 virus (EC50=4.67 µM)[3].Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen, an organoselenium compound, can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity[4][5].
Molecular Weight:
274.18
Purity:
99.91
CAS Number:
[60940-34-3]
Formula:
C13H9NOSe
Target:
Calcium Channel,HIV,Phosphatase,Virus Protease
Application Notes:
MCE Product type: Reference compound
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