Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used to detect Alzheimers disease (AD) and other tau proteinopathies. Its binding sites are located in the beta-helix of the paired helical filaments (PHFs) and straight filaments (SFs) of the tau protein, as well as in the C-shaped cavity of the SFs. In addition, APN-1607 can bind to the intraneuronal inclusions in Alzheimers disease (AD), primary age-related tauopathy (PART), and posterior cortical atrophy (PCA). Florzolotau is expected to be used in PET imaging research of neurological diseases, especially tau proteinopathies[1].
Molecular Weight:
385.46
CAS Number:
[1565797-16-1]
Formula:
C20H20FN3O2S
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Reference compound1
* VAT and and shipping costs not included. Errors and price changes excepted
