Tacrolimus monohydrate (FK506 monohydrate), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex and inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1].
Molecular Weight:
822.03
Purity:
99.93
CAS Number:
[109581-93-3]
Formula:
C44H71NO13
Target:
Antibiotic,Autophagy,Bacterial,FKBP,Phosphatase
Application Notes:
Natural Products
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