(E/Z)-J147 is an exceptionally potent, orally active, neuroprotective agent for cognitive enhancement. (E/Z)-J147 can readily pass the blood brain barrier (BBB). (E/Z)-J147 can inhibit monoamine oxidase B (MAO B) and the dopamine transporter with EC50 values of 1.88 µM and 0.649 µM, respectively. (E/Z)-J147 has potential for the study of Alzheimers disease (AD)[1][2][3].
Molecular Weight:
350.34
Purity:
99.54
CAS Number:
[1146963-51-0]
Formula:
C18H17F3N2O2
Target:
Dopamine Transporter,Monoamine Oxidase
Application Notes:
MCE Product type: Reference compound
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