Pemetrexed (LY231514) disodium hemipenta hydrate is a CNS-penetrant antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
Molecular Weight:
516.41
Purity:
99.78
CAS Number:
[357166-30-4]
Formula:
C20H24N5Na2O8.5
Target:
Antifolate,Apoptosis,Autophagy
Application Notes:
MCE Product type: Reference compound
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