XL-418 is an orally active dual Akt and p70S6K inhibitor with IC50s of 1 nM for Akt1 and 2 nM for p70S6K. XL-418 inhibits the phosphorylation of ribosomal protein S6 and GSK3beta. XL-418 can be used for the study of prostate carcinoma and breast cancer[1].
Molecular Weight:
609.48
CAS Number:
[871343-09-8]
Formula:
C26H32BrF3N8O
Target:
Akt,GSK-3,Ribosomal S6 Kinase (RSK)
Application Notes:
MCE Product type: Reference compound
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