2-O-(p-Nitrophenyl)-alpha-D-N-acetylneuraminic acid (PNP-alpha-NeuNAc) is a classic chromogenic substrate for neuraminidase. 2-O-(p-Nitrophenyl)-alpha-D-N-acetylneuraminic acid releases p-nitrophenol upon enzymatic hydrolysis, allowing quantification of enzyme activity and inhibitory effects via spectrophotometry. 2-O-(p-Nitrophenyl)-alpha-D-N-acetylneuraminic acid (PNP-alpha-NeuNAc) acts as a sialyl donor in the process of enzyme-catalyzed trans-sialylation[1][2].
Molecular Weight:
430.36
CAS Number:
[26112-88-9]
Formula:
C17H22N2O11
Target:
Biochemical Assay Reagents
Application Notes:
MCE Product type: Reference compound
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