Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells[1][2].
Molecular Weight:
354.43
Purity:
99.57
CAS Number:
[304684-77-3]
Formula:
C18H18N4O2S
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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