Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat reduces IFN-alpha, CRP, immune complex deposition, and SARS-CoV-2 viral load. Ezurpimtrostat can be used for the study of systemic lupus erythematosus, SARS-CoV-2, hepatocellular carcinoma, fibrosis, and related disorders[1][2][3][4].
Molecular Weight:
422.99
Purity:
99.37
CAS Number:
[1914148-72-3]
Formula:
C25H31ClN4
Target:
Apoptosis,Autophagy,IFNAR,SARS-CoV
Application Notes:
MCE Product type: Reference compound1
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