7-Acetyl paclitaxel is a microtubule depolymerization inhibitor which inhibits calcium-induced microtubule depolymerization. 7-Acetyl paclitaxel reduces the growth of J774.2 macrophages (IC50 ~ 60 nM) and increases the levels of nitric oxide (NO) and TNF in isolated mouse peritoneal macrophages[1].
Molecular Weight:
895.94
Purity:
98.35
CAS Number:
[92950-39-5]
Formula:
C49H53NO15
Target:
Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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