7ß,27-Dihydroxycholesterol (7beta, 27-OHC) is a potent and selective activator of RORgammat (Ki=120 nM). 7ß,27-Dihydroxycholesterol promotes the differentiation of mouse and human CD4+ Th17 cells. 7ß,27-Dihydroxycholesterol also increases the production of IL-17 depended on CYP27A1[1].
Molecular Weight:
418.65
Purity:
99.58
CAS Number:
[240129-43-5]
Formula:
C27H46O3
Target:
ROR
Application Notes:
MCE Product type: Reference compound
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