NU6027 is a potent and ATP-competitive inhibitor of both CDK1 and CDK2, with Kis of 2.5 µM and 1.3 µM, respectively. NU6027 is also a potent inhibitor of ATR and enhances hydroxyurea and cisplatin cytotoxicity in an ATR-dependent manner[1][2].
Molecular Weight:
251.28
Purity:
99.04
CAS Number:
[220036-08-8]
Formula:
C11H17N5O2
Target:
ATM/ATR,CDK
Application Notes:
MCE Product type: Reference compound
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