Stattic is a potent STAT3 inhibitor and inhibits STAT3 phosphorylation (at Y705 and S727)[1]. Stattic inhibits the binding of a high affinity phosphopeptide for the SH2 domain of STAT3[2]. Stattic ameliorates the renal dysfunction in Alport syndrome (AS) mice[3].
Molecular Weight:
211.19
Purity:
99.58
CAS Number:
[19983-44-9]
Formula:
C8H5NO4S
Target:
Apoptosis,STAT
Application Notes:
MCE Product type: Reference compound
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