KRA-533 is a potent KRAS agonist. KRA-533 binds to the GTP/GDP binding pocket in the KRAS protein to prevent GTP cleavage, resulting in the accumulation of constitutively active GTP-bound KRAS that triggers both apoptotic and autophagic cell death pathways in cancer cells.
Molecular Weight:
314.18
Purity:
98.73
CAS Number:
[10161-87-2]
Formula:
C13H16BrNO3
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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