ADTL-EI1712 is a potent, orally active, and selective dual-target inhibitor of ERK1 and ERK5, inhibition rates of ERK1/5 at 1 µM are 93.54% and 89.35%, respectively. ADTL-EI1712 can induce regulated cell death, a form of cell death that relies on the activation of genetically encoded machinery, to overcome compensatory mechanism in specific cancer cells in vitro and in vivo[1].
Molecular Weight:
505.44
CAS Number:
[2414916-45-1]
Formula:
C22H18Cl2N4O2S2
Target:
ERK
Application Notes:
MCE Product type: Reference compound
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