SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 µM and 45 µM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation[1][2].
Molecular Weight:
302.78
Purity:
99.25
CAS Number:
[312636-16-1]
Formula:
C15H11ClN2OS
Target:
Apoptosis,SphK,Wnt
Application Notes:
MCE Product type: Reference compound
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