DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research[1].
Molecular Weight:
309.68
Purity:
99.82
CAS Number:
[897326-30-6]
Formula:
C13H9ClFN3O3
Target:
HSP
Application Notes:
MCE Product type: Reference compound
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