SY-5609 (CDK7-IN-3) is an orally active, highly selective, noncovalent CDK7 inhibitor with a KD of 0.065 nM. SY-5609 shows poor inhibition on CDK2 (Ki=2600 nM), CDK9 (Ki=960 nM), CDK12 (Ki=870 nM). SY-5609 induces apoptosis in tumor cells and has antitumor activity[1][2].
Molecular Weight:
490.46
Purity:
99.93
CAS Number:
[2417302-07-7]
Formula:
C23H26F3N6OP
Target:
Apoptosis,CDK
Application Notes:
MCE Product type: Reference compound
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