Miclxin (DS37262926) is a potent inhibitor of mutant beta-catenin, involving in Wnt signaling pathway. Miclxin induces beta-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex[1].
Molecular Weight:
441.52
Purity:
98.12
CAS Number:
[2494198-61-5]
Formula:
C26H27N5O2
Target:
Apoptosis,Wnt,beta-catenin
Application Notes:
MCE Product type: Reference compound
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