GSK973, CAS [[2138473-38-6]]

Product Overview

• Article Name: GSK973, CAS [[2138473-38-6]]
• Biozol Catalog Number: MCE-HY-138563
• Supplier Catalog Number: HY-138563
• Alternative Catalog Number: MCE-HY-138563-25MG,MCE-HY-138563-5MG,MCE-HY-138563-10MG,MCE-HY-138563-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK973, a chemical probe, is a highly selective, orally bioavailable inhibitor of the BD2s (second bromodomains) of the BET family, with a pIC50 of 7.8 and a pKd of 8.7 for BRD4 BD2. GSK973 displays a 1600-fold selectivity for BRD4 BD2 over BRD4 BD1. GSK973 shows good potency against BRD2 BD2, BRD3 BD2, and BRDT BD2 (pIC50=7.4~7.8, pKd=8.3~8.5)[1].

Product Properties

• Molecular Weight: 410.44
• Purity: 99.97
• CAS Number: [2138473-38-6]
• Formula: C23H23FN2O4
• Target: Epigenetic Reader Domain

Application Notes

• Application Notes: MCE Product type: Reference compound