Hydroxy Dynasore (Dyngo-4a), a structural mimetic analog of Dynasore (HY-15304), is an improved, less cytotoxic and versatile dynamin inhibitor with IC50 values of 0.38 µM and 2.3 µM for brain recombinant dynamin I and recombinant mouse dynamin II, respectively. Hydroxy Dynasore inhibits dynamin-dependent transferrin endocytosis with an IC50 of 5.7 µM.
Molecular Weight:
338.31
Purity:
99.11
CAS Number:
[1256493-34-1]
Formula:
C18H14N2O5
Target:
Dynamin
Application Notes:
MCE Product type: Reference compound
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