PROTAC BRD4 Degrader-12 (compound 9c) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-12 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.39 nM and 0.24 nM, respectively[1].
Molecular Weight:
1306.58
Purity:
98.54
CAS Number:
[2417370-90-0]
Formula:
C62H77F2N9O12S4
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: ADC Related
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