Vepdegestrant-d5, CAS [[3025452-07-4]] Preis auf Anfrage

Product Overview

• Article Name: Vepdegestrant-d5, CAS [[3025452-07-4]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-138642S
• Supplier Catalog Number: HY-138642S
• Alternative Catalog Number: MCE-HY-138642S-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ARV-471-d5

Product Description

Vepdegestrant-d5 (ARV-471-d5) is the deuterium labeled Vepdegestrant (HY-138642). Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a DC50 of about 2 nM[1].

Product Properties

• Molecular Weight: 728.93
• CAS Number: [3025452-07-4]
• Formula: C45H44D5N5O4
• Target: Isotope-Labeled Compounds

Application Notes

• Application Notes: MCE Product type: Isotope-Labeled Compounds