NCGC00378430 is a potent SIX1/EYA2 interaction inhibitor. NCGC00378430 partially reverses transcriptional and metabolic profiles mediated by SIX1 overexpression and reverses SIX1-induced TGF-beta signaling and epithelial-mesenchymal transition (EMT). NCGC00378430 inhibits SIX1-mediated breast cancer metastasis in a mouse model[1].
Molecular Weight:
441.50
Purity:
99.58
CAS Number:
[920650-00-6]
Formula:
C22H23N3O5S
Target:
Phosphatase
Application Notes:
MCE Product type: Reference compound
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