Zanzalintinib (XL092) is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET, VEGFR2, AXL and MER, with IC50s in cell-based assays of 15 nM, 1.6 nM, 3.4 nM, 7.2 nM respectively. Zanzalintinib exhibits anti-tumor activity. Zanzalintinib has the potential for kinase-dependent diseases and conditions research[1][2].
Molecular Weight:
528.53
Purity:
99.91
CAS Number:
[2367004-54-2]
Formula:
C29H25FN4O5
Target:
c-Met/HGFR,TAM Receptor,VEGFR
Application Notes:
Reference compound
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