ICCB-19 hydrochloride is a TRADD (TNFRSF1A associated via death domain) inhibitor. ICCB-19 hydrochloride binds with N-terminal domain of TRADD (TRADD-N), disrupting its binding to both TRADD-C and TRAF2. ICCB-19 hydrochloride is indirect inhibitor of RIPK1 kinase activity. ICCB-19 hydrochloride effectively induces autophagy and the degradation of long-lived proteins[1].
Molecular Weight:
291.84
Purity:
99.25
CAS Number:
[1803605-68-6]
Formula:
C12H22ClN3OS
Target:
Apoptosis,Autophagy,RIP kinase
Application Notes:
MCE Product type: Reference compound
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