(S,S)-TAK-418 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), demonstrating significant normalization of aberrant gene expression in neurodevelopmental disorders. (S,S)-TAK-418 also ameliorates ASD-like behaviors in rodent models affected by maternal exposure to valproate or poly I:C. (S,S)-TAK-418 modulates gene expression differently across various models and ages, indicating its potential as a therapeutic agent for conditions like autism spectrum disorder and schizophrenia.
Molecular Weight:
356.91
CAS Number:
[1818253-48-3]
Formula:
C17H25ClN2O2S
Target:
Histone Demethylase
Application Notes:
MCE Product type: Reference compound
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