DDN is a selective insulin receptor (Insulin Receptor) activator, an insulin sensitizer, and a glucose-lowering insulin mimetic with oral bioavailability. DDN can directly bind to the receptor kinase domain and induce Akt and ERK phosphorylation, and it can also enhance insulins effect on glucose uptake. DDN significantly reduces blood glucose levels in wild-type and diabetic ob/ob and db/db mice[1].
Molecular Weight:
343.12
CAS Number:
[118006-14-7]
Formula:
C14H8Cl2O6
Target:
Akt,ERK,Insulin Receptor
Application Notes:
MCE Product type: Reference compound
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