Tyrphostin AG1296 is a potent and selective inhibitor of platelet-derived growth factor receptor (PDGFR), with an IC50 of 0.8 µM. Tyrphostin AG1296 inhibits signaling of human PDGF alpha- and beta-receptors as well as of the related stem cell factor receptor (c-Kit). Tyrphostin AG1296 is also a potent inhibitor of FLT3, with an IC50 in the micromolar range[1][2][3].
Molecular Weight:
266.29
Purity:
99.69
CAS Number:
[146535-11-7]
Formula:
C16H14N2O2
Target:
Apoptosis,c-Kit,FLT3,PDGFR
Application Notes:
MCE Product type: Reference compound
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