A-278637 is a selective KATP channel opening agent with an EC50 of 102 nM. A-278637 does not interact with other ion channels, including L-type calcium channels or other neurotransmitter receptor systems. A-278637 possesses a greater functional selectivity for urinary bladder versus vascular smooth muscle in vivo. A-278637 can be used for the study of overactive bladder[1][2].
Molecular Weight:
412.27
CAS Number:
[227609-66-7]
Formula:
C17H15BrFNO3S
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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