GK563 is a selective Ca2+-independent phospholipase A2 (GVIA iPLA2) inhibitor with an IC50 value of 1 nM. GK563 is 22000 times more active against GVIA iPLA2 than GIVA cPLA2. GK563 reduces beta-cell apoptosis induced by proinflammatory cytokines, raising the possibility that it can be beneficial in countering autoimmune diseases, such as type 1 diabetes[1].
Molecular Weight:
246.34
CAS Number:
[2351820-19-2]
Formula:
C16H22O2
Target:
Apoptosis,Phospholipase
Application Notes:
MCE Product type: Reference compound
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