NNMT-IN-6 is a selective nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 1.41 µM and a Kd of 5.55 µM. NNMT-IN-6 hydrochloride exhibits selectivity over PRMT1 and NSD2. NNMT-IN-6 inhibits cancer cell proliferation and reduces cellular N-methylnicotinamide (MNA) production. NNMT-IN-6 can be used for the research of oral cancer[1].
Molecular Weight:
507.54
CAS Number:
[2368247-39-4]
Formula:
C25H29N7O5
Target:
Amine N-methyltransferase
Application Notes:
MCE Product type: Reference compound
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