NNMT-IN-6 hydrochloride is a selective nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 1.41 µM and a Kd of 5.55 µM. NNMT-IN-6 hydrochloride exhibits selectivity over PRMT1 and NSD2. NNMT-IN-6 hydrochloride inhibits cancer cell proliferation and reduces cellular N-methylnicotinamide (MNA) production. NNMT-IN-6 hydrochloride can be used for the research of oral cancer[1].
Molecular Weight:
544.00
Purity:
99.75
CAS Number:
[3031756-18-7]
Formula:
C25H30ClN7O5
Target:
Amine N-methyltransferase
Application Notes:
MCE Product type: Reference compound
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