TDRL-X80 is a potent inhibitor of xeroderma pigmentosum group A (XPA) protein. TDRL-X80 inhibits XPAs DNA binding activity. TDRL-X80 exhibits activity against single, double, and Cisplatin-damaged DNA with IC50s of 18, 20, and 29 µM in fluorescence polarization (FP) analyses , and with IC50s of 21, 39, and 28 in ELISA Analysis[1].
Molecular Weight:
450.83
Purity:
99.6
CAS Number:
[292065-64-6]
Formula:
C23H15ClN2O6
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound
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