MEPB is a modulator of AF-2 of the androgen receptor. MEPB increases co-repressor binding of AR. MEPB can bind to the BF3 pocket of AR specifically, thereby modulating the binding of co-regulators to the AF2 domain. MEPB alleviates degeneration in spinal bulbar muscular atrophy mouse model[1].
Molecular Weight:
404.52
CAS Number:
[331948-99-3]
Formula:
C24H24N2O2S
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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