SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs[1][2].
Molecular Weight:
331.32
Purity:
98.08
CAS Number:
[332063-87-3]
Formula:
C19H13N3O3
Target:
GLUT
Application Notes:
MCE Product type: Reference compound
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