PAD3-IN-1 (compound 14b) is an inhibitor of protein arginine deiminase (PAD) and is more than 10-fold more selective for PAD3 than PAD 1, 2, and 4. The IC50 values of PAD3-IN-1 for PAD 1, 2, 3, and 4 are 120, 27.5, 4.5, and 30.5 µM, respectively. And PAD3 is a PAD isoform associated with neurodegenerative responses to spinal cord injury, and PAD3-IN-1 could be used to study PAD-related neurological diseases[1].
Molecular Weight:
433.33
CAS Number:
[1671088-84-8]
Formula:
C21H22Cl2N4O2
Target:
Protein Arginine Deiminase
Application Notes:
MCE Product type: Reference compound
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