DCH36_06 is a potent and selective p300/CBP inhibitor with IC50s of 0.6 µM and 3.2 µM for p300 and CBP, respectively. DCH36_06 mediated p300/CBP inhibition leading to hypoacetylation on H3K18 in leukemic cells. Anti-tumor activity[1].
Molecular Weight:
372.83
Purity:
99.19
CAS Number:
[593273-05-3]
Formula:
C18H13ClN2O3S
Target:
Apoptosis,Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
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