NiCur is a potent and selective CBP histone acetyltransferase (HAT) inhibitor with an IC50 value of 0.35 µM. NiCur, which blocks CBP HAT activity and downregulates p53 activation upon genotoxic stress. NiCur can be used for performing mechanistic studies without affecting the expression of target proteins[1].
Molecular Weight:
324.38
Purity:
99.11
CAS Number:
[2674753-39-8]
Formula:
C22H16N2O
Target:
Histone Acetyltransferase
Application Notes:
MCE Product type: Reference compound
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