T0467 activates parkin mitochondrial translocation in a PINK1-dependent manner in vitro. T0467 do not induce mitochondrial accumulation of PINK1in dopaminergic neurons. T0467 is a potential compound for PINK1-Parkin signaling activation, and can be used for parkinsons disease and related disorders research[1].
Molecular Weight:
441.49
Purity:
99.30
CAS Number:
[859518-94-8]
Formula:
C24H26F3N5
Target:
Mitochondrial Metabolism,PINK1/Parkin
Application Notes:
MCE Product type: Reference compound
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