CDK12-IN-6, a pyrazolotriazine, is a potent CDK12 inhibitor with an IC50 of 1.19 µM at high ATP (2 mM). CDK12-IN-6 has no effect on CDK2/Cyclin E (IC50>20 µM) and CDK9/Cyclin T1 (IC50>20 µM) at high ATP (2 mM) (WO2021116178A1)[1].
Molecular Weight:
425.44
Purity:
98.09
CAS Number:
[2651196-71-1]
Formula:
C20H21F2N9
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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