Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-beta, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2].
Molecular Weight:
470.47
Purity:
98.14
CAS Number:
[1931994-81-8]
Formula:
C20H21F3N4O4S
Target:
IRAK
Application Notes:
MCE Product type: Reference compound
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