MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2 (HY-137516). LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 µM)[1][2].
Molecular Weight:
662.15
Purity:
99.84
CAS Number:
[2561529-96-0]
Formula:
C34H37ClFN7O4
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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