(rel)-ML-SI3 is one of the active ingredients of ML-SI3 (HY-139426) (another component is (cis)-ML-SI3) that targets three isoforms of TRPML. (rel)-ML-SI3 is an inhibitor of TRPML1 and TRPML3 (IC50=3.1 µM/28.5 µM), and a potent activator of TRPML2 (EC50=3.3 µM)[1][2][3].
Molecular Weight:
429.58
Purity:
98.94
CAS Number:
[2108567-79-7]
Formula:
C23H31N3O3S
Target:
Autophagy,TRP Channel
Application Notes:
MCE Product type: Reference compound1
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