NVP 231 is a potent, specific, and reversible ceramide kinase (CerK) inhibitor(IC50=12 nM) that competitively inhibits binding of ceramide to CerK[1]. NVP 231 induces cell apoptosis by increasing DNA fragmentation and caspase-3 and caspase-9 cleavage[2].
Molecular Weight:
431.55
Purity:
99.73
CAS Number:
[362003-83-6]
Formula:
C25H25N3O2S
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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