Ninerafaxstat (IMB-1018972) is a novel orally active cardiac mitochondrial drug that restores myocardial energy homeostasis. Ninerafaxstat competitively inhibits 3-ketoacyl-CoA thiolase (3-KAT) to partially suppress fatty acid oxidation, and shifts cardiac energy metabolism from free fatty acid oxidation to glucose oxidation, regulating myocardial substrate utilization and thereby improving cardiac efficiency. Ninerafaxstat can be used for research on cardiovascular diseases[1][2].
Molecular Weight:
415.48
Purity:
99.14
CAS Number:
[2254741-41-6]
Formula:
C22H29N3O5
Target:
Mitochondrial Metabolism
Application Notes:
MCE Product type: Reference compound
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